Despite centuries of innovation, chemistry is often still the limiting factor in the development of small molecule drug candidates, molecular probes, or novel chemical libraries. Many molecules that have tremendous biological potential are challenging to modify with known chemical methods. The overarching goal of our program is to develop new methods for the synthesis of molecules that have previously been inaccessible. By developing modular syntheses of intractable molecules, we are able to access unprecedented structural diversity, combat resistance mechanisms, and answer longstanding questions in biology.
Research
Modern chemical synthesis applied to biological challenges.
Publications
A complete listing of our published work.
People
Graduate students are encouraged to apply to the Scripps Graduate Program. Postdoctoral applications should include a CV and a 1-page summary of research accomplishments and should be submitted directly by email to Ian. Currently we do not have any funded postdoctoral positions available; candidates with their own funding are encouraged to apply.